If at first cancer therapies based on surgery, radiation, and chemotherapy side effect bad and uncomfortable, in the future will become increasingly specific therapy and reduced interference on the quality of life for those forced to live it.
Conservative therapy was like an atomic bomb which made the whole body is devastated to get hurt. Patient radiation and chemotherapy, for example, often experience nausea, hair loss, until charred skin. In contrast, more advanced therapies called monoclonal antibodies only shoot targets cancer cells so that, in addition to more effective, side effects are also much reduced.
These days, the mass media in central Europe give place to the researchers at the University of Nottingham, UK, and University of Maastricht, the Netherlands, because of its findings. They managed to manipulate the genetics of soil bacteria that can fight cancer directly at the source.
Ancient Bacteria
Bacteria found in soil was named Clostridium sporogenes. Clostridium is a genus of gram-positive bacteria. As a group of ancient bacteria that has been present on Earth when oxygen-rich atmosphere yet, clostridium requires anaerobic conditions (without oxygen) to produce endospores. The condition is then used to treat cancer experts.
Experts have long understood. Body tissue is generally conditioned aerobic or oxygen-containing, while cancer cells are solid, as in breast cancer, brain, and prostate, there is no oxygen. Thus, Clostridium endospores will breed well in cancerous tissue is dense.
Thus, the experts put the enzyme into the bacterial gene, activating its function as a cancer drug work so endosporanya achieve the conditions without oxygen. Thus, the drugs kill only cancer cells, while cells in the healthy tissue would be safe.
Professor Nigel Minton, who led the study, as quoted by BBC News, stated, "The properties owned by clostridium it is actually a common natural phenomenon, but to be exceptional in the treatment of cancer."
Nell Barrie, a senior staff member at the information agency of Cancer Research UK, echoed Minton. He called this finding as the key to prevention of cancer that has been sought after experts.
Tests on animals had shown encouraging results. Drugs are injected through the blood stream is only active in the section containing the enzyme triggers. However, Barrie reminded that cancer remains a difficult health problems resolved because of the character of each different cancer cells.
Unfortunately, from the time found this method until it is actually used to treat cancer patients still need a long time. Trials in cancer patients, for example, will begin in 2013.
In monoclonal antibody experience, from when she was found Cesar Milstein and Georges Kohler in Cambridge, England, in 1975, it took about ten years until this treatment method could eventually be used for therapy among medical patients.
In addition to monoclonal antibodies, there is also an anticancer drug that contains a "small molecule". These molecules after entry into the cells to function to block signals from the cell wall receptor called tyrosine kinase domain. By blocking the command signal to the nucleus of a cell to divide, cancer cells can be turned off. Drugs "small molecule" is among them to cope with lung and pancreatic cancer.
Problems with
So many efforts to tackle cancer research because until now the disease is still a one cause of death in the world. According to the World Health Organization (WHO), there are 7.6 million cancer deaths in 2008 and increased to an estimated 11 million deaths by 2030.
The results of all efforts is the variety of methods of treatment, conventional or modern-with all its pros and cons. Modern treatment methods are generally effective, but still very expensive. While the conservatives often cause side effects although the cost is relatively cheaper.
In practice, the treatment of cancer is often combined, both between modern medicine and antarpengobatan conservative or conservative. That's why cancer therapies should be administered by a team with a variety of subspecialty, such as specialist hematology, oncology, radiology, and anatomic pathology.
No comments:
Post a Comment