Monday, September 5, 2011

Effect of Diabetes on Brain

Diabetes mellitus affects the entire body, including the brain. Recent research suggests diabetes mellitus (DM) slowing of mental function and increases risk of Alzheimer's disease. Complications that occur in the brain is just one reason why we must control the diabetes.

Scientists are not clear about how type 2 diabetes affects the brain as there are many factors involved.

"High blood sugar may have a direct impact on the nerve cells or cells in the nervous system suport. It could also cause damage to blood vessels large and small. Lainny result is reduced supply of oxygen to the brain thus increasing the risk of stroke," said Alan Jacobson , professor emeritus of psychiatry at Harvard Medical School.

Diabetes mellitus begins with insulin resistance in which fat, muscle and liver cells are unable to use insulin. At first the reaction was pancreas responds by pumping more insulin.

The same enzyme that breaks down insulin also break down a protein called beta-amyloid, formed abnormally in the brains of Alzheimer patients. The more enzymes that work break down insulin, the greater the accumulation of beta-amyloid.

Studies conducted in Sweden found an increased risk of Alzheimer's in people who suffer from diabetes in middle age. Risk of Alzheimer's in people who suffer from diabetes at age 65 is smaller.

"The longer you suffer from diabetes, the higher the risk of Alzheimer's, 'said Margaret Gatz, professor of psychology at the University of Southern California, USA.

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