Behcet disease Cause Blood Vessel Inflammation

Behcet disease is also called Behcet's syndrome is a rare disorder that causes chronic inflammation of the blood vessels throughout the body. The exact cause is unknown, but may be caused by the autoimmune disorder, meaning that the immune system mistakenly attacks the body's healthy cells. Genetic and environmental factors may also be responsible for this Behcet disease.

Behcet disease causes inflammation of various symptoms that may initially seem unrelated. The signs and symptoms of Behcet disease varies from person to person and can come and go alone. Treatment aims to reduce the signs and symptoms of Behcet disease and prevent serious complications, like blindness.

Symptom

Behcet disease symptoms vary person to person. Behcet disease can disappear and appear himself. Signs and symptoms depend on which part of the body are affected by inflammatory disease.

Area of ​​the body commonly affected Behcet disease among others:

1. Mouth
Painful mouth ulcer is the most common sign of Behcet disease is. Sores canker sores usually heal in seven to 21 days although it later reappeared.

2. Skin
Skin problems can vary. Some people have acne-like lesions on the body. Others may include a red rash on the skin soft, especially on the lower leg.

3. Genitals
Sores on the genitals usually occur on the scrotum or vulva. Genital sores are usually painful and can leave scars.

4. Eye
Behcet disease can cause inflammation of the eye called uveitis. Uveitis causes one or both eyes red, pain and blurred vision. Disorder can come and go. Inflammation that occurs in the retinal blood vessels is a serious complication of the disorder.

5. Joints
Swelling and pain in the knee joint. Ankle, elbow or wrist may also be affected. Signs and symptoms can last from one to three weeks and goes away by itself.

6. Circulatory system
Inflammation in blood vessels and large arteries causing swelling, redness, and pain in the arm or leg. Inflammation of the large arteries can lead to complications, such as aneurysms and narrowing or blockage of blood vessels.

7. Digestive System
Behcet disease can cause various signs and symptoms affecting the digestive system including abdominal pain, diarrhea or bleeding.

8. Brain
Behcet disease can cause inflammation in the brain and nervous system that leads to headache, fever, disorders or stroke.

Cause

It is not known what causes Behcet disease. The combination of genetic and environmental factors suspected to be the cause. Some researchers believe that a virus or bacterium may trigger Behcet disease in people who have certain genes that make them susceptible to disease.

Treatments and drugs

There is no cure for this disease. If signs and symptoms of Behcet disease is still mild, doctors can offer medications to control pain and inflammation temporarily.

But if the signs and symptoms are more severe, your doctor may suggest a systemic treatment to control the signs and symptoms of disease throughout the body. Several factors such as age and gender may affect treatment.

Treatment

Behcet disease may come and go it alone in the period of development and the reduction. Doctors will control the signs and symptoms experienced during the progression of the disease with drugs such as:
1. Creams, gels and skin ointments.
These drugs are used directly to sores and genital skin to reduce inflammation and pain. Types of medications usually contain corticosteroids to reduce inflammation or an anesthetic to relieve pain.

2. Special mouthwash that contains corticosteroids and other substances to relieve the pain of mouth sores.

3. Eyedrops
Eye drops containing corticosteroids or anti-inflammatory drugs can reduce pain and redness in the eyes.

Systemic treatment
Severe cases of Behcet disease require treatment to control the damage. Drugs that can be used;
1. Corticosteroids to control inflammation.
The signs and symptoms of Behcet disease is likely to repeat when only treated with corticosteroids. Doctors often prescribe other drugs to suppress the activity of the immune system (immunosuppressive).

2. Immunosuppressive drugs to suppress the immune system overload.
Immunosuppressive drugs is important in controlling Behcet disease, namely cyclosporine azathioprine (Imuran, Azasan), (Sandimmune) and cyclophosphamide (Cytoxan). Because these drugs suppress the immune system, also increases the risk of infection dpat.

3. Drugs that regulate your body's immune system.
Interferon alfa-2b (Intron A) regulate the activity of the immune system to control inflammation. These drugs can help control skin sores, joint pain and inflammation of the eye.

Interferon alpha-2b can be combined with other drugs. More recently, small studies have suggested that drugs that block a substance called tumor necrosis factor (TNF), such as infliximab (Remicade) and etanercept (Enbrel), may be effective in treating some forms of this Behcet disease.

4. Other drugs that have been used to treat Behcet disease include colchicine and methotrexate.